abstract：:Following surgical operations, opiate analgesics are widely used to control pain. This situation was used to investigate patterns of human gastroduodenal motility and the effect of opiate analgesics on this motility during the early postoperative period. Gastric contractions were absent for 6--12 hr following surgery ...

journal_title：Digestive diseases and sciences

authors： Ingram DM,Catchpole BN

更新日期：1981-11-01 00:00:00

abstract：:We explored the hemodynamic effects of rapid injection of 0.9% saline and arterial blood into the canine superior mesenteric artery in anesthetized animals. Mesenteric artery blood flow and pressure were measured in the vessel distal to the site of injection. Injection rates were at or below the rate of blood flow in ...

journal_title：Digestive diseases and sciences

authors： Jacobson ED,Eldon C,Fondacaro JD

更新日期：1981-10-01 00:00:00

abstract：:To ascertain how elevation of the head of the bed, bethanechol, and antacid foam tablets affect gastroesophageal reflux, we used prolonged intraesophageal pH monitoring in 55 symptomatic patients. Acid exposure was separated into reflux frequency and esophageal acid clearance time and recorded during the day in the up...

journal_title：Digestive diseases and sciences

authors： Johnson LF,DeMeester TR

更新日期：1981-08-01 00:00:00

abstract：:A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described. In contrast to the histologic picture of hepatocellular necrosis with or without cholestasis that is generally associated with sulfonamide hepatotoxicity, in the present case a relatively pure cholestatic pattern was fou...

journal_title：Digestive diseases and sciences

authors： Steinbrecher UP,Mishkin S

更新日期：1981-08-01 00:00:00

abstract：:Canine and human exocrine pancreatic secretion into the duodenum during fasting is cyclical and related to intestinal motility. To characterize the composition of pure pancreatic juice during the cyclically recurring sequence of propagated motor events (interdigestive motor complex) and to establish whether pancreatic...

journal_title：Digestive diseases and sciences

authors： Keane FB,Dozois RR,Go VL,Dimagno EP

更新日期：1981-07-01 00:00:00

abstract：:In vitro and in vivo experiments were carried out with medium-chain glycerides. In vitro, cholesterol gallstones were rapidly dissolved by medium-chain glycerides; control experiments with saline solution failed to modify the size of the stones. In vivo, medium-chain glycerides were instilled through an intraductal tu...

journal_title：Digestive diseases and sciences

authors： Uribe M,Uscanga L,Farca S,Sanjurjo JL,LaGarriga J,Ortíz JH

更新日期：1981-07-01 00:00:00

abstract：:Sulfated and unsulfated bile acid composition was studied in serum and bile in 10 patients with alcoholic cirrhosis. Samples, collected before and 2 months after portacaval anastomosis, were analyzed using a gaschromatographic method. Mean total serum bile acid levels rose from 32.0 +/- 5.3 (SE) mumol/liter before to ...

journal_title：Digestive diseases and sciences

authors： Capocaccia L,Attili AF,Cantafora A,Bracci F,Paciscopi L,Puoti C,Pièche U,Angelico M

更新日期：1981-06-01 00:00:00

abstract：:Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary bile acids were separated by chromatography, the majority ...

journal_title：Digestive diseases and sciences

authors： Raedsch R,Lauterburg BH,Hofmann AF

更新日期：1981-05-01 00:00:00

abstract：:The efficacy of tiotidine, a new H2-receptor antagonist, in reducing nocturnal acid secretion of duodenal ulcer patients (N = 12, ages 21-60 years) was investigated. Different doses of tiotidine, 25, 50, 100, and 150 mg or placebo, were given as a single oral dose and acid secretion collected overnight. Tiotidine prod...

journal_title：Digestive diseases and sciences

authors： Valenzuela JE,Strecker RB,Douglas AP

更新日期：1981-05-01 00:00:00

abstract：:Nutrients in the lumen of the small intestine may cause the release of enteric hormones which directly or indirectly stimulate intestinal mucosal growth. Male Sprague-Dawley rats with either an intact small bowel or following jejunal resection were maintained on total parenteral nutrition (TPN). C-terminal octapeptide...

journal_title：Digestive diseases and sciences

authors： Weser E,Bell D,Tawil T

更新日期：1981-05-01 00:00:00

abstract：:Changes in hepatic morphology were evaluated in 242 consecutive liver biopsy specimens obtained from nonalcoholic obese subjects. Steatosis occurred in 59.7% of the subjects but was moderate to severe in 28.7%. An alcoholic hepatitis-like picture was present in 8.7% and cirrhosis in 2.7%. Fibrosis of mild and moderate...

journal_title：Digestive diseases and sciences

authors： Nasrallah SM,Wills CE Jr,Galambos JT

更新日期：1981-04-01 00:00:00

abstract：:When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

journal_title：Digestive diseases and sciences

authors： Kumar R,Nagubandi S,Londowski JM

更新日期：1981-03-01 00:00:00

abstract：:A patient who had a cecostomy because of a complicated appendicitis at the age of 17 functioned with an excluded colon for 47 years. He was then hospitalized for diverticulitis and left pericolic abscess. After treatment of the abscess by left segmental colectomy and reanastomosis, the cecostomy was closed. Two years ...

journal_title：Digestive diseases and sciences

authors： Desechalliers JP,Galmiche JP,Denis P,Teniere P,Testart J,Colin R

更新日期：1981-02-01 00:00:00

abstract：:The effect of insulin on the myoelectric activity of the small intestine was determined in conscious pigs. Animals were implanted with electrodes along the small intestine, a strain gage on the stomach and catheters in both saphenous arteries. Feeding modified the migrating myoelectric complex (MMC), a cyclic pattern ...

journal_title：Digestive diseases and sciences

authors： Rayner V,Weekes TE,Bruce JB

更新日期：1981-01-01 00:00:00

abstract：:An association between hypothermia and gastric ulceration has been reported in rats in cervical cord section and in restraint models. The present study was designed to determine this relationship in cervical and in lumbar cord sectioned Sprague-Dawley rats. Ambient temperatures were varied by placing the sectioned ani...

journal_title：Digestive diseases and sciences

authors： Sigman HH,Gillich A

更新日期：1981-01-01 00:00:00

abstract：:A patient with multiple large hyperplastic (metaplastic) polyps of the colon is reported. Hundreds of polyps, some over 3 cm in size, were distributed uniformly throughout the large bowel. There was no evidence of polyps in the stomach or small intestine. The polyps, except for their large size, had the histologic fea...

journal_title：Digestive diseases and sciences

authors： Sumner HW,Wasserman NF,McClain CJ

更新日期：1981-01-01 00:00:00

abstract：:In recent years, a number of comprehensive reviews have been written on inherited intestinal polyposis syndromes (1-7), but none has dealt specifically with Gardner's syndrome and none has focused on basic research being carried out in an attempt to understand this syndrome and to improve the medical management of aff...

journal_title：Digestive diseases and sciences

authors： Naylor EW,Lebenthal E

更新日期：1980-12-01 00:00:00

abstract：:We present six cases of cancer associated with Crohn's disease and stress the importance of the earlier age of onset than spontaneously arising small-bowel carcinoma, the long period of latency from the time of diagnosis of Crohn's disease to that of carcinoma, and the generally poor prognosis. We emphasize, furthermo...

journal_title：Digestive diseases and sciences

authors： Traube J,Simpson S,Riddell RH,Levin B,Kirsner JB

更新日期：1980-12-01 00:00:00

abstract：:To investigate the possible role of pepsin in ulceration induced by hydrogen ion back-diffusion, the ratio of alkali-labile pepsinogen to total pepsinogen was studied during the course of aspirin- and taurocholate-induced gastric ulceration in comparison with the changes in the ion permeability and histological findin...

journal_title：Digestive diseases and sciences

authors： Ohe K,Yokoya H,Kitaura T,Kunita T,Miyoshi A

更新日期：1980-11-01 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00

abstract：:To evaluate the frequency and type of gastroduodenal mucosal inflammatory changes in patients with symptomatic acid peptic disease and nonulcer dyspepsia, 100 patients with gastrointestinal symptoms indicative of acid peptic disease or dyspepsia and 10 control subjects were clinically evaluated and underwent radiograp...

journal_title：Digestive diseases and sciences

authors： Greenlaw R,Sheahan DG,DeLuca V,Miller D,Myerson D,Myerson P

更新日期：1980-09-01 00:00:00

abstract：:The purpose of the present study is to show anomalies of the plasma cAMP response of patients with hepatic disorders to a single injection of a low dose of glucagon (1 microgram/kg body wt). The response was markedly blunted in patients with liver cirrhosis and potentiated in patients with acute or chronic hepatitis. ...

journal_title：Digestive diseases and sciences

authors： Maekubo H,Matsushima T,Okada F,Honma M,Ui M

更新日期：1980-09-01 00:00:00

abstract：:Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome. ...

journal_title：Digestive diseases and sciences

authors： Barkin JS,Silvis S,Greenwald R

更新日期：1980-08-01 00:00:00

abstract：:Four patients with cold urticaria and six control subjects were studied. Gastric acid output was measured for 1 hr before and 1 hr after the immersion of both hands in ice cold water. The mean acid output fell in the control group by 16.3%. Acid output in the cold urticaria patients rose in each case following the col...

journal_title：Digestive diseases and sciences

authors： Lass N,Doron O,Gilat T

更新日期：1980-07-01 00:00:00

abstract：:A 36-year-old female with a six-year history of Crohn's disease of the anus and colon was found to have in situ cloacogenic carcinoma of the anus after having undergone total proctocolectomy for massive bleeding. This case further supports the association between Crohn's disease of the gastrointestinal tract and its p...

journal_title：Digestive diseases and sciences

authors： Daly JJ,Madrazo A

更新日期：1980-06-01 00:00:00

abstract：:Serum biochemical tests were observed for about three weeks following oral cholecystography with fractionated high doses (6 g) of iopanoic acid (Telepaque) or sodium ipodate (Biloptin) in 24 and 29 patients, respectively. Both agents produced similar effects. No significant changes were seen in renal or hepatic functi...

journal_title：Digestive diseases and sciences

authors： Reiner RG,Lawson MJ,Marshall J,Read TR,Beng CG,Davies GT,Tucker WG,Grant AK

更新日期：1980-05-01 00:00:00

abstract：:Hemorrhage into the biliary tract, known as hemobilia, is discussed almost exclusively in the surgical literature. Internists should also be aware of this entity. Two cases of hemobilia from hepatic artery aneurysm that ruptured into the biliary tract are presented. Both patients developed pancreatitis in addition to ...

journal_title：Digestive diseases and sciences

authors： Kaplan RP,Kaplan L,Panish J,Treiman R

更新日期：1980-02-01 00:00:00

abstract：:A 68-year-old woman developed exfoliative dermatitis while taking cimetidine for gastritis. She had no history of previous drug reactions, allergies, or skin disorders and had taken no other medications for three months. Although cimetidine is a relatively safe drug, severe reactions such as exfoliative dermatitis can...

journal_title：Digestive diseases and sciences

authors： Yantis PL,Bridges ME,Pittman FE

更新日期：1980-01-01 00:00:00

abstract：:Heart failure is a recognized, although uncommon, cause of massive liver cell necrosis, the clinical consequences of which are intermingled with those of cardiac insufficiency in most cases. We report the cases of six patients suffering from chronic heart failure in whom an episode of acute circulatory failure resulte...

journal_title：Digestive diseases and sciences

authors： Nouel O,Henrion J,Bernuau J,Degott C,Rueff B,Benhamou JP

更新日期：1980-01-01 00:00:00

abstract：:A randomized controlled clinical study was conducted to determine (a) whether basic aluminum sucrose sulfate (sucralfate) is effective in preventing or reducing gastric ulcer recurrence, and (b) the clinical parameters contributing to ulcer recurrence after endoscopically proved healing has been effected. A total of 1...

journal_title：Digestive diseases and sciences

authors： Miyake T,Ariyoshi J,Suzaki T,Oishi M,Sakai M,Ueda S

更新日期：1980-01-01 00:00:00

abstract：:In a young woman with Takayasu's arteritis, standard roentgenographic studies suggested a diagnosis of Crohn's ileocolitis. Mesenteric angiography was performed and revealed specific abnormalities diagnostic of Crohn's disease, namely, the zoning sign in the cecum with a hypervascular inner layer and a hypovascular ou...

journal_title：Digestive diseases and sciences

authors： Friedman CJ,Tegtmeyer CJ

更新日期：1979-12-01 00:00:00

abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

journal_title：Digestive diseases and sciences

authors： Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

更新日期：1979-12-01 00:00:00

abstract：:The effects of various nonsteroidal antiinflammatory drugs on the gastric mucosa were endoscopically evaluated in 40 normal volunteers. Eight groups, each containing five subjects were designed: aspirin (3600 mg/d); placebo; ibuprofen (1600 mg/d); ibuprofen (2400 mg/d); indomethacin (100 mg/d); indomethacin (150 mg/d)...

journal_title：Digestive diseases and sciences

authors： Lanza FL,Royer GL Jr,Nelson RS,Chen TT,Seckman CE,Rack MF

更新日期：1979-11-01 00:00:00

abstract：:Squamous cell carcinoma represents the most common primary malignant lesion of the esophagus (1). The initial manifestation of lymphosarcoma infrequently occurs in the gastrointestinal tract, and in one large series, there were no lymphosarcomas presenting in the esophagus (2). In the case described below, a primary h...

journal_title：Digestive diseases and sciences

authors： Berman MD,Falchuk KR,Trey C,Gramm HF

更新日期：1979-11-01 00:00:00

abstract：:Twenty-eight patients with delayed gastric emptying as measured by an abnormal barium "burger" were treated with metoclopramide in a randomized, double-blind fashion. Five had diabetic gastroparesis, four had undergone vagotomy and pyloroplasty, and 19 were idiopathic. Patients received either metoclopramide or placeb...

journal_title：Digestive diseases and sciences

authors： Perkel MS,Moore C,Hersh T,Davidson ED

更新日期：1979-09-01 00:00:00

abstract：:Alterations in insulin and glucagon levels might account for the plasma amino acid imbalance of cirrhotics. In order to verify this hypothesis we evaluated basal insulin, glucagon, branched-chain amino acids, aromatic amino acids, and free tryptophan in 13 controls and 37 cirrhotics divided on the basis of their menta...

journal_title：Digestive diseases and sciences

authors： Marchesini G,Forlani G,Zoli M,Angiolini A,Scolari MP,Bianchi FB,Pisi E

更新日期：1979-08-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:Seven subjects were given one day's treatment with full doses of either aspirin, ibuprofen, or placebo, and then their stomachs were washed out three times at intervals of 10 min, for five successive days. The blood in the recoveries was estimated chemically. After compensating for gastric emptying, the rate of bleedi...

journal_title：Digestive diseases and sciences

authors： Hunt JN

更新日期：1979-07-01 00:00:00

abstract：:Five healthy young adults developed an acute self-limiting ulcerative esophagitis. Two had definite evidence of herpes virus being present and a third one had appropriate changes in herpes simplex viral titer. All cases followed a characteristic and similar course consisting of sudden onset of odynophagia, multiple di...

journal_title：Digestive diseases and sciences

authors： Springer DJ,DaCosta LR,Beck IT

更新日期：1979-07-01 00:00:00

abstract：:The morphine-Prostigmin test (MPT) has been advocated as a diagnostic test for identifying patients with papillary stenosis. We studied 14 patients referred for possible papillary stenosis with the MPT and ERCP sphincter of Oddi manometry. The response to the MPT (symptoms, serum amylase/lipase values) was evaluated b...

journal_title：Digestive diseases and sciences

authors： LoGiudice JA,Geenen JE,Hogan WJ,Dodds WJ

更新日期：1979-06-01 00:00:00